Kian Peng Koh, Akiko Yabuuchi, Sridhar Rao, Yun Huang, Kerrianne Cunniff, Julie Nardone, Asta Laiho, Mamta Tahiliani, Cesar A. Sommer, Gustavo Mostoslavsky, Riitta Lahesmaa, Stuart H. Orkin, Scott J. Rodig, George Q. Daley, Anjana Rao. TET family enzymes convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. Here, we show that Tet1 and Tet2 are Oct4-regulated enzymes that together sustain 5hmC in ….
Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells
Published Friday, December 9, 2011 By admin. Under Uncategorized Tags: 5Hydroxymethylcytosine, cell, Cells, Embryonic, Lineage, Mouse, Production, Regulate, Specification, stem, Tet1, Tet2